Type I Interferon Modulates the Function of Ly6C High-Expressing Naïve CD8<sup>+</sup> T Cells to Promote an Antitumor Response

Type I Interferon Modulates the Function of Ly6C High-Expressing Naïve CD8<sup>+</sup> T Cells to Promote an Antitumor Response

<b>Background:</b> Ly6C expression in naïve CD8+ T cells plays a crucial role in enhancing their effector activity, suggesting potential implications for cancer immunotherapy. This study investigates the functional impact of Ly6C expression on CD8<sup>+</sup> T cells and expl...

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Bibliographic Details
Main Authors: Hsin-Fang Tu, Julia Tao, Ming-Hung Hu, Darrell Fan, Ya-Chea Tsai, Tzyy-Choou Wu, Chien-Fu Hung
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Vaccines
Subjects:
type I interferon
Ly6C<sup>hi</sup> CD8 T cells
immune modulation
cancer immunotherapy
Online Access:https://www.mdpi.com/2076-393X/13/3/246
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