The HL-60 clone 15 cell line as a model for leukocyte migration–possibilities and limitations

The HL-60 clone 15 cell line as a model for leukocyte migration–possibilities and limitations

IntroductionAs a part of the innate immune system, eosinophils are recruited during infectious diseases, to release their characteristic cytotoxic granules and catch pathogens in extracellular traps. Moreover, eosinophils have a crucial role in autoimmune diseases, for example allergies. The isolati...

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Main Authors: Lena Griesbaum, Christopher Weusthof, Thorben Sauer, Timo Gemoll, Gregor Weirich, Ludger Klimek, Julie Petry, Ali Bashiri Dezfouli, Maria Shoykhet, Barbara Wollenberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
eosinophilic differentiation
eosinophil biology
eosinophilic research
immunology
allergy
migration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1515993/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1515993/full

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