IGF2BP2 orchestrates global expression and alternative splicing profiles associated with glioblastoma development in U251 cells

Glioblastoma (GBM) is a highly invasive and malignant central nervous system tumor with a median survival duration of 15 months despite multimodal therapy. The insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) has been implicated in various cancers and is known to regulate RNA metabolism...

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Bibliographic Details
Main Authors: Wenqing Liu, Yan Liu, Haoyuan Li, Shixiong Wang, Pengfei Chen, Zhongtao Liu, Xianhao Huo, Jihui Tian
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Translational Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003036
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