Pre-conditioning with PQQ during pregnancy alleviates LPS-induced placental damage and improves the fetal survival and growth in mice

Pre-conditioning with PQQ during pregnancy alleviates LPS-induced placental damage and improves the fetal survival and growth in mice

BackgroundIntrauterine infection is a major cause of preterm birth, fetal demise, and growth restriction. Placental damage resulting from such infections plays a central role in mediating these adverse outcomes. Pyrroloquinoline quinone (PQQ) is a naturally occurring nutrient known for its antioxida...

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Bibliographic Details
Main Authors: Yongli Han, Yan Zhu, Xiaohui Lu, Tingting Fan, Yina Yin, Pengfei Liu, Xiuliang Dai, Hongbin Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Endocrinology
Subjects:
intrauterine infection
fetal health
pyrroloquinoline quinone
placental damage
pre-conditioning
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1617026/full
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https://www.frontiersin.org/articles/10.3389/fendo.2025.1617026/full

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