Downregulation of the NPY-Y1R system in Grpr neurons results in mechanical and chemical hyperknesis in chronic itch

Chronic itch remains a clinically challenging condition with limited therapeutic efficacy, posing a significant burden on patients' quality of life. Despite its prevalence, the underlying neural mechanisms remain poorly understood. In this study, we explored the synaptic relationships between n...

Full description

Saved in:
Bibliographic Details
Main Authors: Danqing Dai, Zongxi Li, Tiantian Zhao, Zhen Li, Yali Tang, Xiujuan Li, Xiao-Fei Gao, Lize Xiong
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996125000221
Tags: Add Tag
No Tags, Be the first to tag this record!