Upregulation of cholinergic modulators Lypd6 and Lypd6b associated with autism drives anxiety and cognitive decline
Abstract Intellectual disability and autistic features are associated with chromosome region 2q23.q23.2 duplication carrying LYPD6 and LYPD6B genes. Here, we analyzed LYPD6 and LYPD6B expression in patients with different neuropsychiatric disorders. Increased LYPD6 and LYPD6B expression was revealed...
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| Main Authors: | Aizek B. Isaev, Maxim L. Bychkov, Dmitrii S. Kulbatskii, Alexander A. Andreev-Andrievskiy, Mikhail A. Mashkin, Mikhail A. Shulepko, Olga V. Shlepova, Eugene V. Loktyushov, Alexander V. Latanov, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2024-10-01
|
| Series: | Cell Death Discovery |
| Online Access: | https://doi.org/10.1038/s41420-024-02211-z |
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