Improving the production of baculovirus expression vector by overexpression of IE0/IE1 through tandem promoter.

The baculovirus expression vector system, known for its protein production in insect cells and has been criticized for its relatively low expression capacity. IE0/IE1, acknowledged vital early regulators of baculovirus, are indispensable for the virus proliferation and regulate the expression of var...

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Bibliographic Details
Main Authors: Sijun He, Weining Li, Ruirui Zhang, Hao Nan, Wangcheng Song, Xiaodong Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0320182
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