SAP30 promotes clear cell renal cell carcinoma proliferation and inhibits apoptosis through the MT1G axis

Abstract Sin3A-associated protein 30 (SAP30) is a crucial component of the SIN/HDAC histone deacetylase complex and acts as a scaffold that facilitates target gene binding. SAP30 is highly expressed in various tumours; however, its role in renal cell carcinoma (RCC) remains unclear. In our study, we...

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Bibliographic Details
Main Authors: Wei Guo, Shuwen Wang, Zitong Yang, Yu Dong, Zhinan Xia, Wei Xue, Cheng Zhang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:European Journal of Medical Research
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Online Access:https://doi.org/10.1186/s40001-025-02440-7
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