MSC-mediated mitochondrial transfer promotes metabolic reprograming in endothelial cells and vascular regeneration in ARDS

MSC-mediated mitochondrial transfer promotes metabolic reprograming in endothelial cells and vascular regeneration in ARDS

Background Mesenchymal stem cells (MSCs) are a potential therapy for acute respiratory distress syndrome (ARDS), but their mechanisms in repairing mitochondrial damage in ARDS endothelial cells remain unclear.Methods We first examined MSCs’ mitochondrial transfer ability and mechanisms to mouse pulm...

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Bibliographic Details
Main Authors: Jinlong Wang, Shanshan Meng, Yixuan Chen, Haofei Wang, Wenhan Hu, Shuai Liu, Lili Huang, Jingyuan Xu, Qing Li, Xiaojing Wu, Wei Huang, Yingzi Huang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Redox Report
Subjects:
Acute respiratory distress syndrome
mesenchymal stem cells
mitochondria
pulmonary microvascular endothelial cells
tunneling nanotubes
reactive oxygen species
Online Access:https://www.tandfonline.com/doi/10.1080/13510002.2025.2474897
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https://www.tandfonline.com/doi/10.1080/13510002.2025.2474897

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