Structure-based identification of potent fibroblast growth factor receptor 4 (FGFR4) inhibitors as potential therapeutics for hepatocellular carcinoma
Fibroblast growth factor receptor 4 (FGFR4), a member of the fibroblast growth factor receptor family, plays a crucial role in cell growth, differentiation, and tissue repair. Increased FGFR4 expression has been detected in various cancers, including lung, liver, kidney and pancreatic cancer, making...
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| Main Authors: | Lin Fan, Hui Xie, Weiyu Wang, Guizhu Peng, Zhen Fu, Qifa Ye |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
PeerJ Inc.
2025-06-01
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| Series: | PeerJ |
| Subjects: | |
| Online Access: | https://peerj.com/articles/19183.pdf |
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