Structure-based identification of potent fibroblast growth factor receptor 4 (FGFR4) inhibitors as potential therapeutics for hepatocellular carcinoma

Fibroblast growth factor receptor 4 (FGFR4), a member of the fibroblast growth factor receptor family, plays a crucial role in cell growth, differentiation, and tissue repair. Increased FGFR4 expression has been detected in various cancers, including lung, liver, kidney and pancreatic cancer, making...

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Bibliographic Details
Main Authors: Lin Fan, Hui Xie, Weiyu Wang, Guizhu Peng, Zhen Fu, Qifa Ye
Format: Article
Language:English
Published: PeerJ Inc. 2025-06-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/19183.pdf
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