Mitochondria-derived peptide MOTS-c restores mitochondrial respiration in type 2 diabetic heart

IntroductionType 2 diabetes (T2D) is a global epidemic, and heart failure is the primary cause of premature death among T2D patients. Mitochondrial dysfunction has been linked to decreased contractile performance in diabetic heart, partly due to a disturbance in the mitochondrial capacity to supply...

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Bibliographic Details
Main Authors: Toan Pham, Andrew Taberner, Anthony Hickey, June-Chiew Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1602271/full
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