Rutin ameliorates imiquimod-induced psoriasis-like skin lesions by inhibiting oxidative stress injury and the inflammatory response in mice via the Keap1/Nrf2 signaling pathway

Rutin ameliorates imiquimod-induced psoriasis-like skin lesions by inhibiting oxidative stress injury and the inflammatory response in mice via the Keap1/Nrf2 signaling pathway

Abstract Psoriasis is a chronic inflammatory skin disease with a high world-wide incidence. Rutin, a natural citrus flavonoid glycoside, has been shown to have anti-inflammatory and antioxidant properties. To investigate the protective effects of rutin in imiquimod (IMQ)-induced psoriasis model mice...

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Bibliographic Details
Main Authors: Yuan Hu, Xinghua Liang, Xinyue Li, Yingying Han, Guangping Lang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Psoriasis
Rutin
Oxidative stress
Inflammation
Nrf2
Online Access:https://doi.org/10.1038/s41598-025-08451-y
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https://doi.org/10.1038/s41598-025-08451-y

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