Saliva-derived extracellular vesicles: a promising therapeutic approach for salivary gland fibrosis

Abstract Background Salivary gland (SG) fibrosis is characterized by aberrant extracellular matrix deposition and myofibroblast activation, leading to irreversible glandular dysfunction. Current treatments remain ineffective in reversing fibrosis, necessitating novel therapeutic strategies. Methods...

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Bibliographic Details
Main Authors: Boyuan Peng, Xufei Guo, Jialing Kang, Shijiao Pan, Lili Wei, Lianhao Wang, Bo Li, Guangli Han, Yong Cheng
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Journal of Translational Medicine
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Online Access:https://doi.org/10.1186/s12967-025-06620-1
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