Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells

Inhibition of p38-MK2 pathway enhances the efficacy of microtubule inhibitors in breast cancer cells

Microtubule-targeting agents (MTAs) are widely used as first- and second-line chemotherapies for various cancers. However, current MTAs exhibit positive responses only in subsets of patients and are often accompanied by side effects due to their impact on normal cells. This underscores an urgent nee...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu-Chia Chen, Mamoru Takada, Aerica Nagornyuk, Muhan Yu, Hideyuki Yamada, Takeshi Nagashima, Masayuki Ohtsuka, Jennifer G DeLuca, Steven M Markus, Motoki Takaku, Aussie Suzuki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-05-01
Series:eLife
Subjects:
microtubule
cell cycle
p38 MAPK-MK2 signaling
breast cancer
Online Access:https://elifesciences.org/articles/104859
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://elifesciences.org/articles/104859

Similar Items