Demethylating drugs alter protoplast development, regeneration, and the genome stability of protoplast-derived regenerants of cabbage

Abstract Background Methylation is a major DNA modification contributing to the epigenetic regulation of nuclear gene expression and genome stability. DNA methyltransferases (DNMT) inhibitors are widely used in epigenetic and cancer research, but their biological effects and the mechanisms of their...

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Bibliographic Details
Main Authors: Agnieszka Kiełkowska, Agnieszka Brąszewska
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Plant Biology
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Online Access:https://doi.org/10.1186/s12870-025-06473-2
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