Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals

Differential brainstem connectivity according to sex and menopausal status in healthy male and female individuals

Abstract Background Brainstem nuclei play a critical role in both ascending monoaminergic modulation of cortical function and arousal, and in descending bulbospinal pain modulation. Even though sex-related differences in the function of both systems have been reported in animal models, a complete un...

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Main Authors: Lisa A. Kilpatrick, Arpana Church, David Meriwether, Swapna Mahurkar-Joshi, Vince W. Li, Jessica Sohn, Juliana Reist, Jennifer S. Labus, Tien Dong, Jonathan P. Jacobs, Bruce D. Naliboff, Lin Chang, Emeran A. Mayer
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Biology of Sex Differences
Subjects:
Sex differences
Estrogen
Neuroimaging
Brainstem nuclei
Online Access:https://doi.org/10.1186/s13293-025-00709-4
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https://doi.org/10.1186/s13293-025-00709-4

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