Rational design of a NIR fluorescent probe for highly selective sensing of NAD(P)H quinone oxidoreductase 1 in living systems

NAD(P)H quinone oxidoreductase 1 (NQO1) plays a critical role in catalyzing the reduction of quinones, thereby exerting both chemical protection and biological activation. The expression level of NQO1 in various tumor cells, especially glioma, lung cancer, colon cancer and breast cancer cells, is hi...

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Bibliographic Details
Main Authors: Fangyu Yang, Li Zhu, Fei Yan, Houli Zhang, Guobiao Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1626741/full
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