The effect of α-lipoic acid treatment on plasma asymmetric dimethylarginine, a biomarker of endothelial dysfunction in diabetic neuropathy

The effect of α-lipoic acid treatment on plasma asymmetric dimethylarginine, a biomarker of endothelial dysfunction in diabetic neuropathy

Introduction Diabetic neuropathy may develop on a background of hyperglycaemia and is associated with increased oxidative stress. Elevated asymmetric dimethylarginine (ADMA) levels are linked to oxidative stress reducing the synthesis of nitric oxide (NO) by uncoupling NO synthase. Oxidative stress...

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Main Authors: Ferenc Sztanek, Hajnalka Lőrincz, Ágnes Molnár, Anita Szentpéteri, Eszter Zöld, Ildikó Seres, Dénes Páll, Mariann Harangi, Péter Kempler, György Paragh
Format: Article
Language:English
Published: Termedia Publishing House 2020-12-01
Series:Archives of Medical Science
Subjects:
diabetic neuropathy
cardiac autonomic neuropathy
nitric oxide
asymmetric dimethylarginine
a-lipoic acid
Online Access:https://www.archivesofmedicalscience.com/The-effect-of-lipoic-acid-treatment-on-plasma-asymmetric-dimethylarginine-a-biomarker,119785,0,2.html
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