Mutational landscape of the surface antigen of hepatitis B virus in patients with hepatocellular carcinoma

Mutational landscape of the surface antigen of hepatitis B virus in patients with hepatocellular carcinoma

Abstract Mutations within the hepatitis B virus surface antigen (HBsAg) were found to correlate with progressive liver diseases, including hepatocellular carcinoma (HCC). Mutations in this region can impact viral morphogenesis, virus-host interactions, and immune responses. In this cross-sectional s...

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Main Authors: Arwa Bagasi, Fatimah Alghnnam, Marie Bohol, Fatimah Alhamlan, Arwa Al-Qahtani, Hani Alothaid, Ayman Abdo, Faisal Sanai, Ahmad Al-Qahtani
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Gut Pathogens
Subjects:
Chronic HBV
Viral adaptation
HBsAg
Hepatocellular Carcinoma
Online Access:https://doi.org/10.1186/s13099-025-00719-y
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https://doi.org/10.1186/s13099-025-00719-y

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