Downregulation of FASN in granulosa cells and its impact on ovulatory dysfunction in PCOS

Downregulation of FASN in granulosa cells and its impact on ovulatory dysfunction in PCOS

Abstract Background Polycystic ovary syndrome (PCOS) is a complicated endocrinological and anovulatory disorder in women. Mice exposed to dihydrotestosterone (DHT) exhibit a PCOS-like phenotype characterized by abnormal steroid hormone production and ovulation dysfunction. The present investigation...

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Bibliographic Details
Main Authors: Zhaoping Tan, Tiancheng Wu, Mei Wang, Liang Chen, Yating Li, Ming Zhang, Yuanzhen Zhang, Lili Sun
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Ovarian Research
Subjects:
Polycystic ovary syndrome
FASN
Bioinformatic analysis
Ovulatory dysfunction
Online Access:https://doi.org/10.1186/s13048-025-01645-y
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https://doi.org/10.1186/s13048-025-01645-y

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