Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity

Utility of 3-(2-oxo-2H-chromen-3-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde in the synthesis of novel 1,3,4-thiadiazoles or 1,3-thiazoles and study their cytotoxic activity

Abstract One of the biggest causes of death around the world is cancer. Despite the development of a variety of chemotherapeutic drugs that stop excessive cell division, drug resistance remains a major obstacle to chemotherapy. It is consequently critical to develop and find new and effective anti-c...

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Bibliographic Details
Main Authors: Anhar Abdel-Aziem, Abdou O. Abdelhamid
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Coumarin
1,3-thiazole
1,3,4-thiadiazole
Hydrazonoyl halides
Cytotoxic activity
Online Access:https://doi.org/10.1038/s41598-025-13664-2
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https://doi.org/10.1038/s41598-025-13664-2

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