Exploring the biological functions and immune regulatory roles of IRAK3, TNFRSF1A, CX3CR1, and JUNB in T2DM combined with MAFLD: integrated bioinformatics and single-cell analysis

Exploring the biological functions and immune regulatory roles of IRAK3, TNFRSF1A, CX3CR1, and JUNB in T2DM combined with MAFLD: integrated bioinformatics and single-cell analysis

ObjectiveDiabetes mellitus combined with nonalcoholic fatty liver disease is a prevalent and intricate metabolic disorder that presents a significant global health challenge, imposing economic and emotional burdens on society and families. An in-depth understanding of the disease pathogenesis is cru...

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Bibliographic Details
Main Authors: Qin Wang, Xiaoqi Li, Kaidierdan Wushoulaji, Jinyang Wang, Li Wan, Ye Yang, Xueli Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
T2DM
MAFLD
single-cell RNA sequencing
biomarkers
immune signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1587225/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1587225/full

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