The heterogeneity of genomic alterations, metastatic patterns and immune microenvironment in metastatic ovarian cancer originating from colorectal cancer

The heterogeneity of genomic alterations, metastatic patterns and immune microenvironment in metastatic ovarian cancer originating from colorectal cancer

PurposeThe ovarian metastases originating from colorectal cancer (CRCOM) develops rapidly and lethally. Previously, the genetic alterations and metastatic pathway in CRCOM were not well understood. The aim of this study is to explore the special molecular phenotype and dissemination patterns of CRCO...

Full description

Saved in:
Bibliographic Details
Main Authors: Chao Chen, Jian Wang, Binjie Sun, Yuyan Zheng, Xiaoxu Ge, Zhiyuan Gong, Haochen Gu, Zhiwei Zhang, Akao Zhu, Yingkuan Shao, Yeting Hu, Lijia Ma, Yini Li, Kefeng Ding, Da Wang, Lifeng Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
ovarian metastases
colorectal cancer
whole exome sequencing
genetic alterations
phylogenetic tree analysis
metastatic pattern
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593439/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593439/full

Similar Items