THE STUDY OF INTESTINAL PERMEABILITY IN VITRO ON A MONOLAYER OF EPITHELIAL CACO-2 CELLS (REVIEW)

THE STUDY OF INTESTINAL PERMEABILITY IN VITRO ON A MONOLAYER OF EPITHELIAL CACO-2 CELLS (REVIEW)

This paper is devoted to the application of epithelial monolayer of human colon adenocarcinoma cells — Caco-2 for in vitro permeability evaluation of drugs. Main advantages of this biological model are described. General principles, approaches and methodology of Caco-2 permeability assay are defined...

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Bibliographic Details
Main Authors: I. E. Shokhin, G. V. Ramenskaya, Y. I. Kulinich, A. Y. Savchenko
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2012-09-01
Series:Сеченовский вестник
Subjects:
caco-2 cells
permeability
absorption
Online Access:https://www.sechenovmedj.com/jour/article/view/805
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