Discovery and Validation of Novel Biomarkers for Colorectal Neoplasia Detection via Plasma Metabolomics

Discovery and Validation of Novel Biomarkers for Colorectal Neoplasia Detection via Plasma Metabolomics

ABSTRACT Metabolic disturbance plays a critical role in the initiation of colorectal cancer (CRC), yet the identification of metabolites that are useful for early detection of CRC and its precursor lesions remains elusive. We conducted an untargeted plasma metabolomic profiling by liquid chromatogra...

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Main Authors: Jianv Huang, Le Wang, Xiang Zhang, Xinyi Liu, Junyan Miao, Yuefan Shen, Chengqu Fu, Xianxiu Ge, Xue Wang, Jiancong Hu, Guanman Li, Yang Sun, Yinglei Miao, Juncheng Dai, Lingbin Du, Hongxia Ma, Guangfu Jin, Ni Li, Lin Miao, Zhibin Hu, Xiaosheng He, Jun Yu, Hongbing Shen, Dong Hang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:MedComm
Subjects:
biomarkers
colorectal adenoma
colorectal cancer
early diagnosis
metabolomics
Online Access:https://doi.org/10.1002/mco2.70201
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https://doi.org/10.1002/mco2.70201

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