Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study
Green extraction of flavonoids compounds from Vaccinium vitis-idaea L. has received considerable attention due to their potential applications in the food science and biomedical field. In this study, microwave-assisted deep eutectic solvent extraction method was explored to extract total flavone fro...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Green Chemistry Letters and Reviews |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/17518253.2025.2507289 |
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| author | Liying Cui Xiaoyu Li Zhongkai Liu Shengkai Liu Xiaoshuai Wang Mengqi Liu Yujie Fu Zhiguo Liu |
| author_facet | Liying Cui Xiaoyu Li Zhongkai Liu Shengkai Liu Xiaoshuai Wang Mengqi Liu Yujie Fu Zhiguo Liu |
| author_sort | Liying Cui |
| collection | DOAJ |
| description | Green extraction of flavonoids compounds from Vaccinium vitis-idaea L. has received considerable attention due to their potential applications in the food science and biomedical field. In this study, microwave-assisted deep eutectic solvent extraction method was explored to extract total flavone from Vaccinium vitis-idaea L. fruit power. The extraction parameters were optimized response surface experiments. The optimal extraction conditions were as follows: the molar ratio of choline chloride and 1,3-butanediol is 1:1, water content is 50% (V/V), liquid-solid ratio is 15:1 (VmL: Wg), extraction temperature is 55 ℃, and extraction time is 20 min. Under these optimized conditions, the extraction rate of general flavone is 96.29 mg/g, which is 1.47 times high than that of 75% ethanol extraction and 2.33 times than that of pure water extraction under pH = 2.0 conditions. Furthermore, the crude extract obtained by deep eutectic solvent extraction has strong scavenging ability on DPPH free radical, hydroxyl radical and superoxide anion radical. In addituon, the crude extract has efficient antibacterial activity aginst Escherichia coli, Bauman bacillus and Candida albicans. All these results provided the fundmential data for further development of Vaccinium vitis-idaea L. extract as a new natural antioxidant and antibacterial agent. |
| format | Article |
| id | doaj-art-296e524e06b04379a7b23e8bca43fe03 |
| institution | OA Journals |
| issn | 1751-8253 1751-7192 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Green Chemistry Letters and Reviews |
| spelling | doaj-art-296e524e06b04379a7b23e8bca43fe032025-08-20T02:30:09ZengTaylor & Francis GroupGreen Chemistry Letters and Reviews1751-82531751-71922025-12-0118110.1080/17518253.2025.2507289Green extraction of flavone from Vaccinium vitis-idaea L. and their activity studyLiying Cui0Xiaoyu Li1Zhongkai Liu2Shengkai Liu3Xiaoshuai Wang4Mengqi Liu5Yujie Fu6Zhiguo Liu7Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaKey Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin, People’s Republic of ChinaGreen extraction of flavonoids compounds from Vaccinium vitis-idaea L. has received considerable attention due to their potential applications in the food science and biomedical field. In this study, microwave-assisted deep eutectic solvent extraction method was explored to extract total flavone from Vaccinium vitis-idaea L. fruit power. The extraction parameters were optimized response surface experiments. The optimal extraction conditions were as follows: the molar ratio of choline chloride and 1,3-butanediol is 1:1, water content is 50% (V/V), liquid-solid ratio is 15:1 (VmL: Wg), extraction temperature is 55 ℃, and extraction time is 20 min. Under these optimized conditions, the extraction rate of general flavone is 96.29 mg/g, which is 1.47 times high than that of 75% ethanol extraction and 2.33 times than that of pure water extraction under pH = 2.0 conditions. Furthermore, the crude extract obtained by deep eutectic solvent extraction has strong scavenging ability on DPPH free radical, hydroxyl radical and superoxide anion radical. In addituon, the crude extract has efficient antibacterial activity aginst Escherichia coli, Bauman bacillus and Candida albicans. All these results provided the fundmential data for further development of Vaccinium vitis-idaea L. extract as a new natural antioxidant and antibacterial agent.https://www.tandfonline.com/doi/10.1080/17518253.2025.2507289Vaccinium vitis-idaea L. fruit powertotal flavonedeep eutectic solventantioxidationantibacterial |
| spellingShingle | Liying Cui Xiaoyu Li Zhongkai Liu Shengkai Liu Xiaoshuai Wang Mengqi Liu Yujie Fu Zhiguo Liu Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study Green Chemistry Letters and Reviews Vaccinium vitis-idaea L. fruit power total flavone deep eutectic solvent antioxidation antibacterial |
| title | Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study |
| title_full | Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study |
| title_fullStr | Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study |
| title_full_unstemmed | Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study |
| title_short | Green extraction of flavone from Vaccinium vitis-idaea L. and their activity study |
| title_sort | green extraction of flavone from vaccinium vitis idaea l and their activity study |
| topic | Vaccinium vitis-idaea L. fruit power total flavone deep eutectic solvent antioxidation antibacterial |
| url | https://www.tandfonline.com/doi/10.1080/17518253.2025.2507289 |
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