Polygenic risk score prediction accuracy convergence

Polygenic risk score prediction accuracy convergence

Summary: Polygenic risk scores (PRSs) models trained from genome-wide association study (GWAS) results are set to play a pivotal role in biomedical research addressing multifactorial human diseases. The prospect of using these risk scores in clinical care and public health is generating both enthusi...

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Bibliographic Details
Main Authors: Léo Henches, Jihye Kim, Zhiyu Yang, Simone Rubinacci, Gabriel Pires, Clara Albiñana, Christophe Boetto, Hanna Julienne, Arthur Frouin, Antoine Auvergne, Yuka Suzuki, Sarah Djebali, Olivier Delaneau, Andrea Ganna, Bjarni Vilhjálmsson, Florian Privé, Hugues Aschard
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:HGG Advances
Subjects:
polygenic risk prediction
GWAS
sample size
polygenicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247725000600
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http://www.sciencedirect.com/science/article/pii/S2666247725000600

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