Intact HIV DNA decays in children with and without complete viral load suppression.

Intact HIV DNA decays in children with and without complete viral load suppression.

To inform cure in children living with HIV (CWH), we elucidated the dynamics and mechanisms underlying HIV persistence during antiretroviral therapy (ART). In 120 Kenyan CWH who initiated ART between 1-12 months of age, 55 had durable viral load suppression, and 65 experienced ART interruptions. We...

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Main Authors: Daniel B Reeves, Morgan Litchford, Carolyn S Fish, Anna Farrell-Sherman, Makayla Poindexter, Nashwa Ahmed, Noah A J Cassidy, Jillian Neary, Dalton Wamalwa, Agnes Langat, Daisy Chebet, Hellen Moraa, Annukka A R Antar, Jennifer Slyker, Sarah Benki-Nugent, Lillian B Cohn, Joshua T Schiffer, Julie Overbaugh, Grace John-Stewart, Dara A Lehman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013003
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https://doi.org/10.1371/journal.ppat.1013003

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