Effects of realgar-indigo naturalis formula on a zebrafish tumor xenograft model induced by human acute promyelocytic leukemia cells: antitumor activity, hepatotoxicity, and transcriptomic analysis

BackgroundLeukemia is a malignant hematologic disease that poses a serious threat to human health. Realgar-Indigo Naturalis formula (RIF), a traditional Chinese medicine formula, have demonstrated anti-tumor activity, but its mechanisms of action remain unclear.ObjectiveThis study aimed to establish...

Full description

Saved in:
Bibliographic Details
Main Authors: Donghan Bai, Zihao Zhang, Jingyue Gao, Qiaochu Wang, Remy Macdonald, Ziwen Xu, Shumin Chen, Nanxi Huang, Lu Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1619352/full
Tags: Add Tag
No Tags, Be the first to tag this record!