A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis

Abstract It is now appreciated that sphingolipids constitute a rich class of bioactive molecules that include ceramide, sphingosine, and sphingosine 1‐phosphate whose formation is controlled by a network of highly regulated enzymes (Hannun & Obeid, 2008). Notably, several stress stimuli induce t...

Full description

Saved in:
Bibliographic Details
Main Authors: Yusuf A Hannun, Benjamin Newcomb
Format: Article
Language:English
Published: Springer Nature 2015-04-01
Series:EMBO Molecular Medicine
Online Access:https://doi.org/10.15252/emmm.201505161
Tags: Add Tag
No Tags, Be the first to tag this record!