Role of the upper airway microbiota in respiratory virus and bacterial pathobiont dynamics in the first year of life

Role of the upper airway microbiota in respiratory virus and bacterial pathobiont dynamics in the first year of life

Abstract The mechanisms by which respiratory viruses predispose to secondary bacterial infections remain poorly characterized. Using 2,409 nasopharyngeal swabs from 300 infants enrolled in a prospective cohort study in Botswana, we perform a detailed analysis of factors that influence the dynamics o...

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Main Authors: Matthew S. Kelly, Pixu Shi, Sifelane C. Boiditswe, Emily Qin, Andrew P. Steenhoff, Tiny Mazhani, Mohamed Z. Patel, Coleen K. Cunningham, John F. Rawls, Kathy Luinstra, Jodi Gilchrist, Julia Maciejewski, Jillian H. Hurst, Patrick C. Seed, David Bulir, Marek Smieja
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-60552-4
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https://doi.org/10.1038/s41467-025-60552-4

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