Evaluation of performance and matrix compatibility of mixed mode C18-SCX SPME fibers for compounds with different physicochemical properties

Evaluation of performance and matrix compatibility of mixed mode C18-SCX SPME fibers for compounds with different physicochemical properties

Solid-phase microextraction (SPME) has evolved significantly since its inception, yet challenges remain in developing coatings fully compatible with LC-MS that combine broad polarity coverage with biocompatibility for complex matrices. This study evaluates mixed-mode C18-SCX (strong cation exchange)...

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Bibliographic Details
Main Authors: Marcos Tascon, Ezel Boyaci, Nathaly Reyes-Garcés, Janusz Pawliszyn
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Advances in Sample Preparation
Subjects:
Bioanalysis
Liquid chromatography
Mass spectrometry
Mixed-mode fibers
SPME LC-tips
Online Access:http://www.sciencedirect.com/science/article/pii/S2772582025000488
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http://www.sciencedirect.com/science/article/pii/S2772582025000488

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