Orthotopic meningioma rat model exhibits morphological and immunohistochemical congruency and epigenetic concordance with benign primary patient-derived tumors
Abstract Meningiomas are the most common primary central nervous system tumor. Clinical trials have failed to support effective medical treatments, despite initially promising animal studies. A key issue could be that available experimental models fail to mimic the clinical situation. Hence, there i...
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| Main Authors: | Mikkel Schou Andersen, Bo Halle, Martin Wirenfeldt, Jeanette Krogh Petersen, Morten Winkler Møller, Philipp Jurmeister, Birgitte Brinkmann Olsen, Bjarne Winther Kristensen, Henning Boldt, Christian Bonde Pedersen, Tiit Mathiesen, Frantz Rom Poulsen |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-12-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-024-83456-7 |
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