Double versus single blastocyst biopsy and vitrification in preimplantation genetic testing (PGT) cycles: protocol for a systematic review and meta-analysis of clinical and neonatal outcomes

Double versus single blastocyst biopsy and vitrification in preimplantation genetic testing (PGT) cycles: protocol for a systematic review and meta-analysis of clinical and neonatal outcomes

Abstract Background The number of re-biopsied blastocysts is widely increasing in IVF cycles and concerns regarding retesting, which involves double biopsy and vitrification-warming, have been raised. The re-biopsy intervention seems to significantly reduce the pregnancy potential of a blastocyst bu...

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Bibliographic Details
Main Authors: Alessandra A. Vireque, Vasileios Stolakis, Thalita S. Berteli, Maria C. Bertero, Jason Kofinas
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Systematic Reviews
Subjects:
Genetic testing/methods
PGT
Biopsy/adverse effects
Trophectoderm biopsy
Re-biopsy
Rewarming/adverse effects
Online Access:https://doi.org/10.1186/s13643-025-02846-8
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https://doi.org/10.1186/s13643-025-02846-8

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