Safety and efficacyof the combination of copanlisib and nivolumab in patients with Richter’s transformation or transformed non-Hodgkin lymphoma: results from a phase I trial

Safety and efficacyof the combination of copanlisib and nivolumab in patients with Richter’s transformation or transformed non-Hodgkin lymphoma: results from a phase I trial

Despite advances in targeted and cellular therapies, outcomes for patients with Richter’s transformation (RT) and transformed non-Hodgkin lymphoma (tNHL) remain dismal. In this study we report safety and efficacy of the combination of the selective, small molecule inhibitor of phosphoinositide-3-ki...

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Main Authors: Geoffrey Shouse, Canping Chen, Alexandra Muir, Leslie Popplewell, Tanya Siddiqi, Jasmine Zain, Alex F. Herrera, Olga Danilova, Carly Roleder, Lili Wang, Stephen E.F. Spurgeon, Adam S. Kittai, Lu Chen, Zheng Xia, Matthew S. Davids, Alexey V. Danilov
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-07-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/12148
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https://haematologica.org/article/view/12148

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