MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint

IntroductionMre11 is a multisubunit nuclease involved in DNA repair, and its dysfunction often causes DNA damage sensitivity, genomic instability, telomere shortening, and aberrant meiosis. However, the specific roles of Mre11 in porcine oocyte meiosis remain unclear.MethodsIn this study, porcine oo...

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Bibliographic Details
Main Authors: Dandan Zhang, Zaishan Yang, Yongteng Zhang, Fugui Fang, Hongguo Cao, Yunsheng Li, Zubing Cao, Yanfeng Xue, Mianqun Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1635110/full
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