The microenvironment cell index is a novel indicator for the prognosis and therapeutic regimen selection of cancers

The microenvironment cell index is a novel indicator for the prognosis and therapeutic regimen selection of cancers

Abstract Background It is worthwhile to establish a prognostic prediction model based on microenvironment cells (MCs) infiltration and explore new treatment strategies for triple-negative breast cancer (TNBC). Methods The xCell algorithm was used to quantify the cellular components of the TNBC micro...

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Main Authors: Xian-Yan Yang, Nian Chen, Qian Wen, Yu Zhou, Tao Zhang, Ji Zhou, Cheng-Hui Liang, Li-Ping Han, Xiao-Ya Wang, Qing-Mei Kang, Xiao-Xia Zheng, Xue-Jia Zhai, Hong-Ying Jiang, Tian-Hua Shen, Jin-Wei Xiao, Yu-Xin Zou, Yun Deng, Shuang Lin, Jiang-Jie Duan, Jun Wang, Shi-Cang Yu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Translational Medicine
Subjects:
Triple-negative breast cancer
Tumor microenvironment
Cell infiltration
Spatial location
Prognosis prediction
Therapeutic regimen
Online Access:https://doi.org/10.1186/s12967-024-05950-w
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https://doi.org/10.1186/s12967-024-05950-w

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