Impact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosis.

Understanding the ecology of drug-resistant pathogens is essential for devising rational programs to preserve the effective lifespan of antimicrobial agents and to abrogate epidemics of drug-resistant organisms. Mathematical models predict that strain fitness is an important determinant of multidrug...

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Bibliographic Details
Main Authors: Sebastian Gagneux, Marcos V Burgos, Kathryn DeRiemer, Antonio Encisco, Samira Muñoz, Phillip C Hopewell, Peter M Small, Alexander S Pym
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-06-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0020061&type=printable
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