A surrogate in vitro experimental model for off-label drug repurposing: inhibitory effect of montelukast on bovine respiratory syncytial virus replication

A surrogate in vitro experimental model for off-label drug repurposing: inhibitory effect of montelukast on bovine respiratory syncytial virus replication

Abstract Background Repurposing off-label drugs during epidemics or pandemics with unknown/known pathogens, particularly when their side effects and complications are already known, can be a strategic approach, as seen during the COVID-19 pandemic. Developing surrogate in vitro experimental models (...

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Bibliographic Details
Main Authors: Hanne Nur Kurucay, Zafer Yazici, Vahide Bayrakal, Bahadir Muftuoglu, Emre Ozan, Cuneyt Tamer, Seda Gozel, Gerald Barry, Mahir Igde, Semra Okur-Gumusova, Harun Albayrak, Ahmed Eisa Elhag, Huseyin Baskin
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Virology Journal
Subjects:
Antiviral
Epidemic
Leukotriene receptor antagonist
Montelukast sodium
Pandemic
RSV
Online Access:https://doi.org/10.1186/s12985-025-02647-4
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https://doi.org/10.1186/s12985-025-02647-4

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