Role of Nitric Oxide in Cardioprotection by Poloxamer 188

Role of Nitric Oxide in Cardioprotection by Poloxamer 188

Poloxamer (P) 188 attenuates myocardial ischemia/reperfusion injury through cell membrane stabilization. Cell–cell interactions between endothelial cells (ECs) and cardiomyocytes (CMs) further protect CMs: co-cultures showed that, at an optimal density, ECs protected CMs against hypoxia/reoxygenatio...

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Bibliographic Details
Main Authors: Zhu Li, Matthew B. Barajas, Takuro Oyama, Matthias L. Riess
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Cells
Subjects:
calcium
cardiomyocyte
co-culture
co-polymer
cross-talk
endothelium
Online Access:https://www.mdpi.com/2073-4409/14/13/1001
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