Systemic inflammatory responses to repeated and increasing endotoxin challenges in fetal sheep

Abstract Repeated low‐dose administration of lipopolysaccharide (LPS) attenuates subsequent fetal responses, which makes it challenging to investigate interventions to prolonged exposure. Our aim was to develop a fetal inflammatory response syndrome (FIRS) model that consistently and effectively eli...

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Bibliographic Details
Main Authors: Sanya Kathuria, Akash Gupta, Ayna R. Tracy, Rosa I. Luna Ramirez, Senthil Kumar Thulasingam, Nahla Zaghloul, Mohamed Ahmed, Sean W. Limesand
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.70316
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