Overcoming Therapeutic Resistance of Triple Positive Breast Cancer with CDK4/6 Inhibition

Triple positive breast cancers overexpress both the human epidermal growth factor receptor 2 (HER2) oncogene and the hormonal receptors (HR) to estrogen and progesterone. These cancers represent a unique therapeutic challenge because of a bidirectional cross-talk between the estrogen receptor alpha...

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Bibliographic Details
Main Authors: Troy B. Schedin, Virginia F. Borges, Elena Shagisultanova
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Breast Cancer
Online Access:http://dx.doi.org/10.1155/2018/7835095
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