Decomposing the effect of normal aging and Alzheimer’s disease in brain morphological changes via learned aging templates

Abstract Alzheimer’s disease (AD) subjects usually show more profound morphological changes with time compared to cognitively normal (CN) individuals. These changes are the combination of two major biological processes: normal aging and AD pathology. Investigating normal aging and residual morpholog...

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Bibliographic Details
Main Authors: Jingru Fu, Daniel Ferreira, Örjan Smedby, Rodrigo Moreno
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-96234-w
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