Intestinal microbiota modulates pancreatic carcinogenesis through intratumoral natural killer cells

Preclinical data demonstrate that the gut microbiota can promote pancreatic ductal adenocarcinoma (PDAC), but mechanisms remain unclear. We hypothesized that intestinal microbiota alters anti-tumor innate immunity response to facilitate PDAC progression. Human PDAC L3.6pl cells were heterotopically...

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Bibliographic Details
Main Authors: Qin Yu, Rachel C. Newsome, Mark Beveridge, Maria C. Hernandez, Raad Z. Gharaibeh, Christian Jobin, Ryan M. Thomas
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Gut Microbes
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Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2022.2112881
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