Interpreting expression data with metabolic flux models: predicting Mycobacterium tuberculosis mycolic acid production.

Metabolism is central to cell physiology, and metabolic disturbances play a role in numerous disease states. Despite its importance, the ability to study metabolism at a global scale using genomic technologies is limited. In principle, complete genome sequences describe the range of metabolic reacti...

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Bibliographic Details
Main Authors: Caroline Colijn, Aaron Brandes, Jeremy Zucker, Desmond S Lun, Brian Weiner, Maha R Farhat, Tan-Yun Cheng, D Branch Moody, Megan Murray, James E Galagan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000489&type=printable
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