The metabolome of fecal extracellular vesicles in patients with malignant solid tumors

The metabolome of fecal extracellular vesicles in patients with malignant solid tumors

Abstract Dysregulated metabolism, a hallmark of cancer, creates unique metabolic features that can be employed to elucidate cancer prognosis, personalized treatment, and therapeutic response. Metabolomics has emerged as a powerful tool for profiling biomarkers in cancer studies. Most cancer metabolo...

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Main Authors: Surbhi Mishra, Arina Maltseva, Anni I. Nieminen, Mikael Niku, Sonja Karikka, Jenni Hekkala, Sirpa Leppä, Pia Vihinen, Kaisa Sunela, Jussi Koivunen, Arja Jukkola, Ilja Kalashnikov, Päivi Auvinen, Okko-Sakari Kääriäinen, Juha Saarnio, Sanna Meriläinen, Tero Rautio, Raila Aro, Reetta Häivälä, Peeter Karihtala, Terhi Ruuska-Loewald, Justus Reunanen
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Gut microbiome
Extracellular vesicles
Metabolome
Cancer, Small-molecule metabolites
Mass spectrometry
Online Access:https://doi.org/10.1038/s41598-025-14250-2
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https://doi.org/10.1038/s41598-025-14250-2

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