Enhancing Physiological Realism in Nasal Spray Deposition Studies: Synthetic Mucus Properties and Interactions with Saline Solutions and Stereolithography Resin

Enhancing Physiological Realism in Nasal Spray Deposition Studies: Synthetic Mucus Properties and Interactions with Saline Solutions and Stereolithography Resin

This study investigated the role of synthetic mucus coatings in enhancing the physiological relevance of in vitro nasal spray deposition assessments using 3D-printed nasal cavity models. Synthetic mucus solutions, representing normal (0.25% <i>w</i>/<i>v</i> xanthan gum) and...

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Bibliographic Details
Main Authors: Amr Seifelnasr, Farhad Zare, Xiuhua Si, Jinxiang Xi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Liquids
Subjects:
synthetic mucus
xanthan gum
liquid film translocation
3D-printing
SLA resin
surface tension
Online Access:https://www.mdpi.com/2673-8015/5/2/11
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