Comprehensive analysis of protein post-translational modifications reveals PTPN2-STAT1-AOX axis-mediated tumor progression in hepatocellular carcinomas

Comprehensive analysis of protein post-translational modifications reveals PTPN2-STAT1-AOX axis-mediated tumor progression in hepatocellular carcinomas

Hepatocellular carcinoma (HCC) is a common malignant tumor. Although the proteomics of HCC is well studied, the landscape of post-translational modifications (PTMs) in HCC is poorly understood. The PTMs themselves and their crosstalk might be deeply involved in HCC development and progression. Herei...

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Main Authors: Junli Wang, Yu Lou, Xiaojun Peng, Mao Ye, Wanyue Cao, Jiangchao Wu, Zhihui Yan, Xiaowen Zhao, Yu Zhou, Chenlei Zheng, Xiaobao Wei, Qitai Chen, Chengyang Hu, Mingxuan Zhang, Lanqing Qu, Zeshe Chen, Qihan Fu, Weixin Wang, Jingsong Li, Qi Zhang, Tingbo Liang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Translational Oncology
Subjects:
Proteomic
Post-translational modification
Histone
CDK2
Liver cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523325000063
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