D‐Aspartate treatment attenuates myelin damage and stimulates myelin repair

D‐Aspartate treatment attenuates myelin damage and stimulates myelin repair

Abstract Glutamate signaling may orchestrate oligodendrocyte precursor cell (OPC) development and myelin regeneration through the activation of glutamate receptors at OPC‐neuron synapses. D‐Aspartate is a D‐amino acid exerting modulatory actions at glutamatergic synapses. Chronic administration of D...

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Main Authors: Valeria de Rosa, Agnese Secondo, Anna Pannaccione, Roselia Ciccone, Luigi Formisano, Natascia Guida, Roberta Crispino, Annalisa Fico, Roman Polishchuk, Antimo D'Aniello, Lucio Annunziato, Francesca Boscia
Format: Article
Language:English
Published: Springer Nature 2018-12-01
Series:EMBO Molecular Medicine
Subjects:
cuprizone
D‐Aspartate
NCX3
oligodendrocytes
remyelination
Online Access:https://doi.org/10.15252/emmm.201809278
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https://doi.org/10.15252/emmm.201809278

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